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Human Genome Central - spring board for Human genome data

Human Genome Central

Spring board for Human genome data

From: The International Human Genome Sequencing Consortium

In the context of the completion of the "Working Draft" of the Human Genome Sequence by the public Human Genome Project, here are some URLs that are good starting points for working with the data.

ResourceLocationNotes
 
Ensembl http://www.ensembl.org
Ensembl allows access to DNA and protein sequences with automatic baseline annotation.
NCBI http://www.ncbi.nlm.nih.gov/genome/guide/ Can view chromosomes and maps and loci with links to other NCBI resources.
Oak Ridge Genome Channel http://compbio.ornl.gov/channel/ Contains Java viewers for Human genome data.
BLAST searches against Draft data http://www.ensembl.org/Data/blast.html
http://www.ncbi.nlm.nih.gov/genome/seq/page.cgi?F=HsBlast.html&&ORG=Hs
Search protein or DNA sequence against human draft data.
The SNP consortium http://snp.cshl.org/ Includes a variety of ways to query for SNPs in the human genome.
OMIM http://www.ncbi.nlm.nih.gov/Omim/ OMIM contains information about human genes and disease.
Gene Map '99 (NCBI) http://www.ncbi.nlm.nih.gov/genemap99/ Gene map 99 contains data and viewers for radiation hybrid maps.
Human genome maps http://genome.wustl.edu/projects/human/index.php?fpc=1 This page contains links to clone and accession maps of the human genome.
Human Genome Project Working Draft Sequence - UCSC http://genome.cse.ucsc.edu/ This page contains an assembly of the current draft of the human genome.
Ethical, Legal, and Social Issues http://www.ornl.gov/hgmis/elsi/elsi.html
http://www.genome.gov/page.cfm?pageID=10001618
Contains information, links and articles on a wide range of issues.
 

The vast majority of the human genome is now publicly available. About 25% of the genome is in finished form, while the great majority of the remainder is in draft form. A publication on the working draft will be submitted later this year.

As with other organisms, the full primary source data is available in each of three public databases: Genbank, EMBL and DDBJ. The information is being searched and analyzed by tens of thousands of scientists in academia and industry.

Still, it is a daunting and time-consuming task for users to directly analyze the primary source data. Many users would like access to ancillary information and tools that provide an ongoing picture of the genome that is both comprehensive and comprehensible. Such information includes the overlaps between clones; the correct genomic location of each clone; an integrated genomic sequence that merges the individual clones; and annotation of gene content.

In fact, such resources have been developed and are freely available - but they are not widely known.

For ease of access, we have created a master web site called "Human Genome Central" containing a brief listing of links to some of the most useful public resources; further links to additional sites can be found within them. The web sites will be regularly updated with new information.

Human Genome Central can be found on both the NCBI and EBI sites at:

www.ncbi.nlm.nih.gov/genome/central
www.ensembl.org/genome/central




 Date : Mon Sep 8 07:05:29 2008 Help Desk / Suggestions